ist rune

An Ist rune is a mid tier rune that can be socketed into armor and weapons in Diablo 2: Lord of Destruction and Diablo 2 Resurrected. An Ist rune provides 25% Better Chance of Getting Magic Items when inserted in shields or off-hands, body armor and headgear, and 30% Better Chance of Getting Magic Items in weapons.

You can cube 2 Mal runes and an amethyst together to get an Ist rune. You can also obtain an Ist rune from hell countess. You can get an Ist rune from the hell hellforge quest.

An Ist rune requires level 51 to use. When you socket an item with an Ist rune, you increase the level requirement to level 51, unless it was already higher.

Clvl 51
weapon30% Better Chance of Getting Magic Itemsarmor/helm25% Better Chance of Getting Magic Itemsshield25% Better Chance of Getting Magic Items
rune sources

Countess:

Hell and above

Hellforge:

Hell

Treasure class:

Act 5 (N) Good

Cube:

2 Mal Rune + Amethyst

Horadric cube recipes with ist runes

upgrade rune

Ist Rune
Ist Rune
sapphire
horadric cube interface

Drop Chance

An Ist rune will drop from TC Runes 12, which is accessed through Runes 13, Act 5 (N) Good or Countess Rune (H). Learn more about Treasure Classes here.

Act 5 (N) Good

Jewelry C
Chipped Gem
Flawed Gem
Normal Gem
Flawless Gem
Runes 12

Runes 12

Mal Rune
Ist Rune
Runes 11

There are 8 runewords that contain an ist rune

list of all runewords in Diablo 2 made with an ist rune
Runeword
Sockets
Allowed BasesRuneword Recipe
Level
Stats
Delirium3 socketshelm
lem runelem + ist runeist + io runeio
51
1% Chance To Cast level 50 Delirium When Struck6% Chance To Cast level 14 Mind Blast When Struck14% Chance To Cast level 13 Terror When Struck11% Chance To Cast level 18 Confuse On Striking+2 To All Skills+261 Defense+10 To Vitality (io)50% Extra Gold From Monsters (lem)25% Better Chance of Getting Magic Items (ist)Level 17 Attract (60 Charges)
Silence6 socketsweapon
dol runedol + eld runeeld + hel runehel + ist runeist + tir runetir + vex runevex
55
+2 to All Skills+20% Increased Attack Speed+20% Faster Hit Recovery+200% Enhanced Damage+75% Damage To Undead (eld)+50 to Attack Rating Against Undead (eld)11% Mana Stolen Per Hit (vex)Hit Blinds Target +33Hit Causes Monster to Flee 25% (dol)All Resistances +75+2 to Mana After Each Kill (tir)30% Better Chance of Getting Magic Items (ist)Requirements -20% (hel)
Call to Arms5 socketsweapon
amn runeamn + ral runeral + mal runemal + ist runeist + ohm runeohm
57
+1 To All Skills+40% Increased Attack Speed+240-290% Enhanced Damage (varies) (ohm)Adds 5-30 Fire Damage (ral)7% Life Stolen Per Hit (amn)+2-6 To Battle Command (varies)+1-6 To Battle Orders (varies)+1-4 To Battle Cry (varies)Prevent Monster Heal (mal)Replenish Life +1230% Better Chance of Getting Magic Items (ist)
Exile4 socketspaladin shield
vex runevex + ohm runeohm + ist runeist + dol runedol
57
15% Chance To Cast Level 5 Life Tap On StrikingLevel 13-16 Defiance Aura When Equipped (varies)+2 To Offensive Auras (Paladin Only)+30% Faster Block RateFreezes Target+220-260% Enhanced Defense (varies)Replenish Life +7 (dol)+5% To Maximum Cold Resist (ohm)+5% To Maximum Fire Resist (vex)25% Better Chance Of Getting Magic Items (ist)Repairs 1 Durability every 4 seconds
Chains of Honor4 socketsbody armor
dol runedol + um runeum + ber runeber + ist runeist
63
+2 To All Skills+200% Damage To Demons+100% Damage To Undead8% Life Stolen Per Hit+70% Enhanced Defense+20 To StrengthReplenish Life +7 (dol)All Resistances +65 (um)Damage Reduced By 8% (ber)25% Better Chance of Getting Magic Items (ist)
Eternity5 socketsmelee weapon
amn runeamn + ber runeber + ist runeist + sol runesol + sur runesur
63
Indestructible+260-310% Enhanced Damage (varies)+9 To Minimum Damage (sol)7% Life Stolen Per Hit (amn)20% Chance of Crushing Blow (ber)Hit Blinds Target (sur)Slows Target By 33%Replenish Mana 16%Cannot Be Frozen30% Better Chance Of Getting Magic Items (ist)Level 8 Revive (88 Charges)
Infinity4 socketspolearmspear
ber runeber + mal runemal + ber runeber + ist runeist
63
50% Chance To Cast Level 20 Chain Lightning When You Kill An EnemyLevel 12 Conviction Aura When Equipped+35% Faster Run/Walk+255-325% Enhanced Damage (varies)-45-55% To Enemy Lightning Resistance (varies)40% Chance of Crushing Blow (ber)Prevent Monster Heal (mal)+(0.5*Clvl) To Vitality (Based on Character Level)30% Better Chance of Getting Magic Items (ist)Level 21 Cyclone Armor (30 Charges)
Obsession6 socketsstaff
zod runezod + ist runeist + lem runelem + lum runelum + io runeio + nef runenef
69
Indestructible (zod)24% Chance to cast level 10 Weaken when struck+4 To All Skills+65% Faster Cast Rate+60% Faster Hit RecoveryKnockback (nef)+10 To Vitality (io)+10 To Energy (lum)Increase Maximum Life 15-25% (varies)Regenerate Mana 15-30% (varies)All Resistances +60-70 (varies)75% Extra Gold from Monsters (lem)30% Better Chance of Getting Magic Items (ist)

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