ist rune

An Ist rune is a mid tier rune that can be socketed into armor and weapons in Diablo 2: Lord of Destruction and Diablo 2 Resurrected. An Ist rune provides 25% Better Chance of Getting Magic Items when inserted in shields or off-hands, body armor and headgear, and 30% Better Chance of Getting Magic Items in weapons.

You can cube 2 Mal runes and an amethyst together to get an Ist rune. You can also obtain an Ist rune from hell countess. You can get an Ist rune from the hell hellforge quest.

An Ist rune requires level 51 to use. When you socket an item with an Ist rune, you increase the level requirement to level 51, unless it was already higher.

Clvl 51
weapon30% Better Chance of Getting Magic Itemsarmor/helm25% Better Chance of Getting Magic Itemsshield25% Better Chance of Getting Magic Items
rune sources


hell and above



Treasure class:

act 5 (nm) good and above


2 mal + amethyst

Horadric cube recipes with ist runes

ist runeist rune
gul runegul rune

    There are 8 runewords that contain an ist rune

    list of all runewords in Diablo 2 made with an ist rune
    Allowed BasesRuneword Recipe
    Delirium3 socketshelm
    lem + ist + io
    1% Chance To Cast level 50 Delirium When Struck6% Chance To Cast level 14 Mind Blast When Struck14% Chance To Cast level 13 Terror When Struck11% Chance To Cast level 18 Confuse On Striking+2 To All Skills+261 Defense+10 To Vitality (io)50% Extra Gold From Monsters (lem)25% Better Chance of Getting Magic Items (ist)Level 17 Attract (60 Charges)
    Silence6 socketsweapon
    dol + eld + hel + ist + tir + vex
    +2 to All Skills+20% Increased Attack Speed+20% Faster Hit Recovery+200% Enhanced Damage+75% Damage To Undead (eld)+50 to Attack Rating Against Undead (eld)11% Mana Stolen Per Hit (vex)Hit Blinds Target +33Hit Causes Monster to Flee 25% (dol)All Resistances +75+2 to Mana After Each Kill (tir)30% Better Chance of Getting Magic Items (ist)Requirements -20% (hel)
    Call to Arms5 socketsweapon
    amn + ral + mal + ist + ohm
    +1 To All Skills+40% Increased Attack Speed+240-290% Enhanced Damage (varies) (ohm)Adds 5-30 Fire Damage (ral)7% Life Stolen Per Hit (amn)+2-6 To Battle Command (varies)+1-6 To Battle Orders (varies)+1-4 To Battle Cry (varies)Prevent Monster Heal (mal)Replenish Life +1230% Better Chance of Getting Magic Items (ist)
    Exile4 socketspaladin shield
    vex + ohm + ist + dol
    15% Chance To Cast Level 5 Life Tap On StrikingLevel 13-16 Defiance Aura When Equipped (varies)+2 To Offensive Auras (Paladin Only)+30% Faster Block RateFreezes Target+220-260% Enhanced Defense (varies)Replenish Life +7 (dol)+5% To Maximum Cold Resist (ohm)+5% To Maximum Fire Resist (vex)25% Better Chance Of Getting Magic Items (ist)Repairs 1 Durability every 4 seconds
    Chains of Honor4 socketsbody armor
    dol + um + ber + ist
    +2 To All Skills+200% Damage To Demons+100% Damage To Undead8% Life Stolen Per Hit+70% Enhanced Defense+20 To StrengthReplenish Life +7 (dol)All Resistances +65 (um)Damage Reduced By 8% (ber)25% Better Chance of Getting Magic Items (ist)
    Eternity5 socketsmelee weapon
    amn + ber + ist + sol + sur
    Indestructible+260-310% Enhanced Damage (varies)+9 To Minimum Damage (sol)7% Life Stolen Per Hit (amn)20% Chance of Crushing Blow (ber)Hit Blinds Target (sur)Slows Target By 33%Replenish Mana 16%Cannot Be Frozen30% Better Chance Of Getting Magic Items (ist)Level 8 Revive (88 Charges)
    Infinity4 socketspolearmspear
    ber + mal + ber + ist
    50% Chance To Cast Level 20 Chain Lightning When You Kill An EnemyLevel 12 Conviction Aura When Equipped+35% Faster Run/Walk+255-325% Enhanced Damage (varies)-45-55% To Enemy Lightning Resistance (varies)40% Chance of Crushing Blow (ber)Prevent Monster Heal (mal)+(0.5*Clvl) To Vitality (Based on Character Level)30% Better Chance of Getting Magic Items (ist)Level 21 Cyclone Armor (30 Charges)
    Obsession6 socketsstaff
    zod + ist + lem + lum + io + nef
    Indestructible (zod)24% Chance to cast level 10 Weaken when struck+4 To All Skills+65% Faster Cast Rate+60% Faster Hit RecoveryKnockback (nef)+10 To Vitality (io)+10 To Energy (lum)Increase Maximum Life 15-25% (varies)Regenerate Mana 15-30% (varies)All Resistances +60-70 (varies)75% Extra Gold from Monsters (lem)30% Better Chance of Getting Magic Items (ist)