ist rune

Diablo 2 Resurrected ist rune

An ist rune is a mid tier rune that can be socketed into armor and weapons. You can cube 2 mal runes and an amethyst together to get an ist rune. You can also obtain an ist rune from hell countess. You can get an ist rune from the hell hellforge quest.

An ist rune requires level 51 to use.

Clvl 51
weapon30% Better Chance of Getting Magic Itemsarmor/helm25% Better Chance of Getting Magic Itemsshield25% Better Chance of Getting Magic Items

Horadric cube recipes with ist runes

  • transmute 2 ist runes and a sapphire to create a gul rune

all runes

There are 7 runewords that contain an ist rune

a-z
level
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  • Clvl 57

    amn - ral - mal - ist - ohm

    Call to Arms is most popular for allowing any character to cast Battle Orders and Battle Command.

    Allowed equipment

    +1 To All Skills+40% Increased Attack Speed+240-290% Enhanced Damage (varies) (ohm)Adds 5-30 Fire Damage (ral)7% Life Stolen Per Hit (amn)+2-6 To Battle Command (varies)+1-6 To Battle Orders (varies)+1-4 To Battle Cry (varies)Prevent Monster Heal (mal)Replenish Life +1230% Better Chance of Getting Magic Items (ist)
  • Clvl 63

    dol - um - ber - ist

    The best base for Chains of Honor is an elite light armor. Dusk Shroud, Wyrmhide, Scarab Husk, Wire Fleece, Great Hauber... more about Chains of Honor

    Allowed equipment

    +2 To All Skills+200% Damage To Demons+100% Damage To Undead8% Life Stolen Per Hit+70% Enhanced Defense+20 To StrengthReplenish Life +7 (dol)All Resistances +65 (um)Damage Reduced By 8% (ber)25% Better Chance of Getting Magic Items (ist)
  • Clvl 51

    lem - ist - io

    Allowed equipment

    1% Chance To Cast lvl 50 Delirium When Struck6% Chance To Cast lvl 14 Mind Blast When Struck14% Chance To Cast lvl 13 Terror When Struck11% Chance To Cast lvl 18 Confuse On Striking+2 To All Skills+261 Defense+10 To Vitality (io)50% Extra Gold From Monsters (lem)25% Better Chance of Getting Magic Items (ist)Level 17 Attract (60 Charges)
  • Clvl 63

    amn - ber - ist - sol - sur

    Allowed equipment

    Indestructible+260-310% Enhanced Damage (varies)+9 To Minimum Damage (sol)7% Life Stolen Per Hit (amn)20% Chance of Crushing Blow (ber)Hit Blinds Target (sur)Slows Target By 33%Replenish Mana 16%Cannot Be Frozen30% Better Chance Of Getting Magic Items (ist)Level 8 Revive (88 Charges)
  • Clvl 57

    vex - ohm - ist - dol

    The best base item for Exile is an Ethereal e-bugged paladin shield with 45 to all resistances (not in D2R)

    Allowed equipment

    15% Chance To Cast Level 5 Life Tap On StrikingLevel 13-16 Defiance Aura When Equipped (varies)+2 To Offensive Auras (Paladin Only)+30% Faster Block RateFreezes Target+220-260% Enhanced Defense (varies)Replenish Life +7 (dol)+5% To Maximum Cold Resist (ohm)+5% To Maximum Fire Resist (vex)25% Better Chance Of Getting Magic Items (ist)Repairs 1 Durability every 4 seconds
  • Clvl 63ladder only

    ber - mal - ber - ist

    When using Infinity for a mercenary, the best base is an ethereal (Giant) thresher. Infinity is most often used for its ... more about Infinity

    Allowed equipment

    50% Chance To Cast Level 20 Chain Lightning When You Kill An EnemyLevel 12 Conviction Aura When Equipped+35% Faster Run/Walk+255-325% Enhanced Damage (varies)-(45-55)% To Enemy Lightning Resistance (varies)40% Chance of Crushing Blow (ber)Prevent Monster Heal (mal)+(0.5*Clvl) To Vitality (Based on Character Level)30% Better Chance of Getting Magic Items (ist)Level 21 Cyclone Armor (30 Charges)
  • Clvl 55

    dol - eld - hel - ist - tir - vex

    Allowed equipment

    +2 to All Skills+20% Increased Attack Speed+20% Faster Hit Recovery+200% Enhanced Damage+75% Damage To Undead (eld)+50 to Attack Rating Against Undead (eld)11% Mana Stolen Per Hit (vex)Hit Blinds Target +33Hit Causes Monster to Flee 25% (dol)All Resistances +75+2 to Mana After Each Kill (tir)30% Better Chance of Getting Magic Items (ist)Requirements -20% (hel)
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