io rune

Diablo 2 Resurrected io rune

An io rune is a low tier rune that can be socketed into armor and weapons. You can cube 3 hel runes and a chipped diamond together to get an io rune. You can also obtain an io rune from nightmare countess. You can get an io rune from the nightmare hellforge quest.

An io rune requires level 35 to use.

Clvl 35
weapon+10 to Vitalityarmor/helm+10 to Vitalityshield+10 to Vitality

Horadric cube recipes with io runes

  • transmute 3 io runes and a flawed topaz to create a lum rune

all runes

There are 6 runewords that contain an io rune

a-z
level
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  • Clvl 35

    thul - io - nef

    The high amount of Crushing Blow, Enhanced Damage, and Increased Attack Speed, makes this weapon a viable choice for mel... more about Black

    Allowed equipment

    +15% Increased Attack Speed+120% Enhanced Damage+200 to Attack RatingAdds 3-14 Cold Damage (3 sec) (thul)40% Chance of Crushing BlowKnockback (nef)+10 to Vitality (io)Magic Damage Reduced By 2Level 4 Corpse Explosion (12 Charges)
  • Clvl 51

    lem - ist - io

    Allowed equipment

    1% Chance To Cast lvl 50 Delirium When Struck6% Chance To Cast lvl 14 Mind Blast When Struck14% Chance To Cast lvl 13 Terror When Struck11% Chance To Cast lvl 18 Confuse On Striking+2 To All Skills+261 Defense+10 To Vitality (io)50% Extra Gold From Monsters (lem)25% Better Chance of Getting Magic Items (ist)Level 17 Attract (60 Charges)
  • Clvl 65ladder only

    io - jah - pul

    Allowed equipment

    Both10% Chance To Cast Level 15 Confuse When StruckLevel 15 Holy Shock Aura When Equipped+20-30% Faster Hit Recovery (varies)+30% Enhanced Defense (pul)+150-220 Defense (varies)+10 To Vitality (io)+(0.625*Clvl) To Mana (Based On Character Level)All Resistances +5-20 (varies)12-25% Better Chance of Getting Magic Items (varies)HeadgearIncrease Maximum Life 5% (jah)Shields+50 To Life (jah)
  • Clvl 37

    lum - io - sol - eth

    Staves can have up to 3 staff modifiers specific to Sorceress spells ranging between +1 and +3 to skill level. Therefore... more about Memory

    Allowed equipment

    +3 To Sorceress Skill Levels+33% Faster Cast Rate+9 To Minimum Damage (sol)-25% Target Defense (eth)+3 To Energy Shield (Sorceress Only)+2 To Static Field (Sorceress Only)+50% Enhanced Defense+10 to Vitality (io)+10 to Energy (lum)Increase Maximum Mana 20%Magic Damage Reduced By 7
  • Clvl 67ladder only

    cham - sur - io - lo

    Allowed equipment

    25% Chance To Cast Level 17 Fire Wall When StruckLevel 16-20 Concentration Aura When Equipped (varies)260-300% Bonus To Attack Rating (varies)+(1*Clvl)% Damage To Demons (Based on Character Level)Adds 50-280 Lightning Damage20% Deadly Strike (lo)Hit Blinds Target (sur)Freezes Target +3 (cham)+10 To Vitality (io)Replenish Life +8(1.875*Clvl)% Extra Gold From Monsters (Based on Character Level)
  • Clvl 35

    dol - io

    Wands can have up to 3 staff modifiers specific to Necromancers spells ranging between +1 and +3 to skill level. Therefo... more about White

    Allowed equipment

    +3 to Poison and Bone Skills (Necromancer Only)+20% Faster Cast Rate+2 to Bone Spear (Necromancer Only)+4 to Skeleton Mastery (Necromancer Only)+3 to Bone Armor (Necromancer Only)Hit causes monster to flee 25% (dol)+10 to vitality (io)+13 to manaMagic Damage Reduced by 4
all runewords