nef rune

A Nef rune is a low tier rune that can be socketed into armor and weapons in Diablo 2: Lord of Destruction and Diablo 2 Resurrected. A Nef rune provides +30 Defense vs. Missile when inserted in shields or off-hands, body armor and headgear, and Knockback in weapons.

You can cube 3 Tir runes together to get a Nef rune. You can also obtain a Nef rune from normal countess. You can get a Nef rune from the normal hellforge quest.

A Nef rune requires level 13 to use. When you socket an item with a Nef rune, you increase the level requirement to level 13, unless it was already higher.

Clvl 13

low rune

weaponKnockbackarmor/helm+30 Defense vs. Missileshield+30 Defense vs. Missile

rune sources
Countess:	Normal and above
Hellforge:	Normal
Treasure class:	Act 2 Good
Cube:	3 Tir Rune

Horadric cube recipes with nef runes

upgrade rune

Crafting recipes with nef runes

Blood Gloves

Caster Mask

Hitpower Armor

Safety Shield

Drop Chance

A Nef rune will drop from TC Runes 2, which is accessed through Runes 3 or Act 2 Good. Learn more about Treasure Classes here.

Act 2 Good

Runes 2

There are 8 runewords that contain a nef rune

list of all runewords in Diablo 2 made with a nef rune
Runeword	Sockets	Allowed Bases	Runeword Recipe	Level	Stats
Nadir	2 sockets	helm	nef + tir	13	+50% Enhanced Defense+10 Defense+30 Defense vs. Missile (nef)+5 to Strength+2 to Mana after each Kill (tir)-33% Extra Gold from Monsters-3 to Light RadiusLevel 13 Cloak of Shadows (9 charges)
Radiance	3 sockets	helm	nef + sol + ith	27	+75% Enhanced Defense+30 Defense vs. Missile (nef)+10 to Vitality+10 to Energy+33 to ManaDamage Reduced by 7 (sol)Magic Damage Reduced by 315% Damage Taken Goes to Mana (ith)+5 to Light Radius
Myth	3 sockets	armor	hel + amn + nef	33	3% Chance To Cast Level 1 Howl When Struck10% Chance To Cast Level 1 Taunt On Striking+2 To Barbarian Skill Levels+30 Defense Vs. Missile (nef)Replenish Life +10Attacker Takes Damage of 14 (amn)Requirements -15% (hel)
Black	3 sockets	club, hammer, mace	thul + io + nef	35	+15% Increased Attack Speed+120% Enhanced Damage+200 to Attack RatingAdds 3-14 Cold Damage (thul)40% Chance of Crushing BlowKnockback (nef)+10 to Vitality (io)Magic Damage Reduced By 2Level 4 Corpse Explosion (12 Charges)
Smoke	2 sockets	armor	nef + lum	37	+20% Faster Hit Recovery+75% Enhanced Defense+280 Defense vs. Missile (nef)+10 to Energy (lum)All Resistances +50-1 to Light RadiusLevel 6 Weaken (18 charges)
Melody	3 sockets	missile weapon	shael + ko + nef	39	+3 To Bow and Crossbow Skills (Amazon Only)+20% Increased Attack Speed (shael)+50% Enhanced Damage+300% Damage To Undead+3 To Slow Missiles (Amazon Only)+3 To Dodge (Amazon Only)+3 To Critical Strike (Amazon Only)Knockback (nef)+10 To Dexterity (ko)
Flickering Flame	3 sockets	helm	nef + pul + vex	55	Level 4-8 Resist Fire Aura When Equipped (varies)+3 to Fire Skills-10-15% to Enemy Fire Resistance (varies)+30% Enhanced Defense (pul)+30 Defense vs. Missile (nef)Adds 3-14 Cold Damage+50-75 to Mana (varies)+5% to Maximum Fire Resist (vex)Half Freeze DurationPoison Length Reduced by 50%
Obsession	6 sockets	staff	zod + ist + lem + lum + io + nef	69	Indestructible (zod)24% Chance to cast level 10 Weaken when struck+4 To All Skills+65% Faster Cast Rate+60% Faster Hit RecoveryKnockback (nef)+10 To Vitality (io)+10 To Energy (lum)Increase Maximum Life 15-25% (varies)Regenerate Mana 15-30% (varies)All Resistances +60-70 (varies)75% Extra Gold from Monsters (lem)30% Better Chance of Getting Magic Items (ist)