nef rune

A Nef rune is a low tier rune that can be socketed into armor and weapons in Diablo 2: Lord of Destruction and Diablo 2 Resurrected. A Nef rune provides +30 Defense vs. Missile when inserted in shields or off-hands, body armor and headgear, and Knockback in weapons.

You can cube 3 Tir runes together to get a Nef rune. You can also obtain a Nef rune from normal countess. You can get a Nef rune from the normal hellforge quest.

A Nef rune requires level 13 to use. When you socket an item with a Nef rune, you increase the level requirement to level 13, unless it was already higher.

Clvl 13
weaponKnockbackarmor/helm+30 Defense vs. Missileshield+30 Defense vs. Missile
rune sources


Normal and above



Treasure class:

Act 2 Good


3 Tir Rune

Horadric cube recipes with nef runes

upgrade rune

Nef Rune
Nef Rune
Nef Rune
horadric cube interface

Crafting recipes with nef runes

Blood Gloves

Vampirebone Gloves
nef Rune
Magic Jewel
Perfect Ruby
horadric cube interface

Caster Mask

nef Rune
Magic Jewel
Perfect Amethyst
horadric cube interface

Hitpower Armor

Kraken Shell
nef Rune
Magic Jewel
Perfect Sapphire
horadric cube interface

Safety Shield

nef Rune
Magic Jewel
Perfect Emerald
horadric cube interface

Drop Chance

A Nef rune will drop from TC Runes 2, which is accessed through Runes 3 or Act 2 Good. Learn more about Treasure Classes here.

Act 2 Good

Jewelry B
Chipped Gem
Flawed Gem
Runes 1
Runes 2

Runes 2

Tir Rune
Nef Rune
Runes 1

There are 8 runewords that contain a nef rune

list of all runewords in Diablo 2 made with a nef rune
Allowed BasesRuneword Recipe
Nadir2 socketshelm
nef runenef + tir runetir
+50% Enhanced Defense+10 Defense+30 Defense vs. Missile (nef)+5 to Strength+2 to Mana after each Kill (tir)-33% Extra Gold from Monsters-3 to Light RadiusLevel 13 Cloak of Shadows (9 charges)
Radiance3 socketshelm
nef runenef + sol runesol + ith runeith
+75% Enhanced Defense+30 Defense vs. Missile (nef)+10 to Vitality+10 to Energy+33 to ManaDamage Reduced by 7 (sol)Magic Damage Reduced by 315% Damage Taken Goes to Mana (ith)+5 to Light Radius
Myth3 socketsarmor
hel runehel + amn runeamn + nef runenef
3% Chance To Cast Level 1 Howl When Struck10% Chance To Cast Level 1 Taunt On Striking+2 To Barbarian Skill Levels+30 Defense Vs. Missile (nef)Replenish Life +10Attacker Takes Damage of 14 (amn)Requirements -15% (hel)
Black3 socketsclubhammermace
thul runethul + io runeio + nef runenef
+15% Increased Attack Speed+120% Enhanced Damage+200 to Attack RatingAdds 3-14 Cold Damage (thul)40% Chance of Crushing BlowKnockback (nef)+10 to Vitality (io)Magic Damage Reduced By 2Level 4 Corpse Explosion (12 Charges)
Smoke2 socketsarmor
nef runenef + lum runelum
+20% Faster Hit Recovery+75% Enhanced Defense+280 Defense vs. Missile (nef)+10 to Energy (lum)All Resistances +50-1 to Light RadiusLevel 6 Weaken (18 charges)
Melody3 socketsmissile weapon
shael runeshael + ko runeko + nef runenef
+3 To Bow and Crossbow Skills (Amazon Only)+20% Increased Attack Speed (shael)+50% Enhanced Damage+300% Damage To Undead+3 To Slow Missiles (Amazon Only)+3 To Dodge (Amazon Only)+3 To Critical Strike (Amazon Only)Knockback (nef)+10 To Dexterity (ko)
Flickering Flame3 socketshelm
nef runenef + pul runepul + vex runevex
Level 4-8 Resist Fire Aura When Equipped (varies)+3 to Fire Skills-10-15% to Enemy Fire Resistance (varies)+30% Enhanced Defense (pul)+30 Defense vs. Missile (nef)Adds 3-14 Cold Damage+50-75 to Mana (varies)+5% to Maximum Fire Resist (vex)Half Freeze DurationPoison Length Reduced by 50%
Obsession6 socketsstaff
zod runezod + ist runeist + lem runelem + lum runelum + io runeio + nef runenef
Indestructible (zod)24% Chance to cast level 10 Weaken when struck+4 To All Skills+65% Faster Cast Rate+60% Faster Hit RecoveryKnockback (nef)+10 To Vitality (io)+10 To Energy (lum)Increase Maximum Life 15-25% (varies)Regenerate Mana 15-30% (varies)All Resistances +60-70 (varies)75% Extra Gold from Monsters (lem)30% Better Chance of Getting Magic Items (ist)