Destruction Runeword

May 25, 2026


Runes
Item Types	Polearm Sword
Ladder Only?	No
Level Required	65
Patch	1.10 - Current
Expansion	Lord of Destruction
15% Chance to cast level 22 Nova on attack100% Chance to cast level 45 Meteor when you Die28% Chance to cast level 35 Molten Boulder on strikingIgnore Target's DefenseAdds 100-180 Magic Damage7% Mana stolen per hit20% Chance of Crushing Blow20% Deadly StrikePrevent Monster Heal+10 to Dexterity+350% Enhanced Damage

Destruction is a Diablo 2 Resurrected Runeword created by combining Vex + Lo + Ber + Jah + Ko into 5 socket Polearm or Sword. It requires at least level 65 to equip. Destruction was first released in patch 1.10.

The Destruction Runeword has quite a few spell procs and can be amusing to use. But, for the very high cost of Vex, Lo, Ber, and Jah runes, it is never worth it to create. The better and much cheaper option to use when creating a build around skill procs is the Rift Runeword.