Plague Runeword

Plague boosting poison skill damage.
Runes
Cham RuneShael RuneUm Rune
Item Types
SwordKnifeHand to Hand
D2R Ladder Only?No
RotW Ladder Only?No
Level Required67
Patch2.4 - Current
ExpansionLord of Destruction
25% Chance to cast level 15 Poison NovaPoison Nova on striking20% Chance to cast level 12 Lower ResistLower Resist when struckLevel 13 to 17 CleansingCleansing Aura When Equipped+1 to 2 to All Skills+20% Increased Attack Speed-23% to Enemy Poison Resistance0.375% Deadly Strike (Based on Character Level)25% Chance of Open WoundsFreezes Target +3+220 to 320% Enhanced Damage

Plague is a Diablo 2 Resurrected Runeword created by combining Cham + Shael + Um into 3 socket Sword, Knife or Hand to Hand. It requires at least level 67 to equip. Plague was first released in patch 2.4.

The Plague Runeword is a high level weapon Runeword released in patch 2.4. It is one of the Runewords that were in the original game files, but were disabled. Blizzard had announced 10 new Runewords for patch 1.11, but only 7 made it in the final release (excluding Plague).

The allowed gear initially changed from all weapons to Swords only, this severely limited the usability and was a missed opportunity to give a solid Runeword for Claws and Daggers.

Plague Bases

Sword10DamageDmgSpeedSpeedStrStrDexDexLvlLvlEarliest drop with 3 OSDrops
Phase BladeLvl 54
31 – 35-302513654
Conquest SwordLvl 58
37 – 53014211258
Cryptic SwordLvl 61
5 – 77-109910961
Mythical SwordLvl 66
40 – 50014712466
Knife2DamageDmgSpeedSpeedStrStrDexDexLvlLvlEarliest drop with 3 OSDrops
Fanged KnifeLvl 62
15 – 57-20428662
Legend SpikeLvl 66
31 – 47-10656766
Hand to Hand5DamageDmgSpeedSpeedStrStrDexDexLvlLvlEarliest drop with 3 OSDrops
SuwayyahLvl 44
39 – 520999944
Wrist SwordLvl 46
34 – 45-1010510546
Feral ClawsLvl 58
22 – 53-2011311358
Runic TalonsLvl 60
24 – 44-3011511560
Scissors SuwayyahLvl 64
40 – 51011811864

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